About

Brand Name - Venclyxto

Generic Name - Venetoclax

Manufacturer - Abbvie 

Dosage Form - Tablets

Strength - 100mg 

Indication - Blood Cancer

Storage - Store at room temperature. 

Venclyxto is an anti-cancer medicine available by prescription. It is used in the treatment of certain types of blood cancers. This drug is prescribed to treat mainly small lymphocytic lymphoma, chronic lymphocytic leukemia, and acute myeloid leukemia. It is available in the strength of 100mg as tablets for oral use. Venclyxto contains Venetoclax that belongs to the class of B-cell lymphoma-2 (BCL-2) inhibitors. It is a kind of targeted therapy medicine.

Pharmacodynamics

Venetoclax promotes rapid and extensive apoptosis of CLL cells, which can happen in 24 hours and result in tumor lysis syndrome. Patients with relapsed CLL (chronic lymphocytic leukemia) or SLL (small lymphocytic leukemia), even those with poor prognostic features, responded well to venetoclax, a drug that selectively targets BCL2. This medication is not expected to influence the cardiac QT interval.